Bioactive Small Molecules
A vast array of small, non-peptide, organic compounds that are biologically active. Products include receptor antagonists, molecular probes, metabolites, GPCR ligands, neurotransmitters, ion channel modulators, and signaling activators and inhibitors.
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16
Tocris Bioscience™ Yoda 1
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Piezo1 channel activator
| Target | Other Calcium Channel Activators |
|---|---|
| CAS | 448947-81-7 |
| Purity | >99% |
| Chemical Name or Material | 2-[5-[[(2,6-Dichlorophenyl)methyl]thio]-1,3,4-thiadiazol-2-yl]pyrazine |
| Recommended Storage | Store at 4°C |
| Molecular Formula | C13H8Cl2N4S2 |
| Formula Weight | 355.27 |
17
Tocris Bioscience™ Y-27632 in solution
Sterile-filtered 10mM solution of Y-27632 pre-dissolved in water
18
Tocris Bioscience™ N-Acetylcysteine
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Glutathione (GSH) precursor; maintains stem cell function in culture.
19
Invitrogen™ BODIPY™ FL Prazosin
Localize and detect the a1-adrenergic receptor
Encompass Procurement Services
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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20
Tocris Bioscience™ Clozapine N-oxide dihydrochloride
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Activator of muscarinic DREADDs; water soluble version of Clozapine N-oxide (Cat. No. 4936)
| Target | DREADD Activators |
|---|---|
| CAS | 2250025-93-3 |
| Purity | 99% |
| Chemical Name or Material | 8-Chloro-11-(4-methyl-4-oxido-1-piperazinyl)-5 H-dibenzo[b,e][1,4 ]diazepine dihydrochloride |
| Recommended Storage | Desiccate at Room Temperature |
| Molecular Formula | C18H19ClN4O0.2 HCl |
| Formula Weight | Observed MW: 415.74 |
| Assay Percent Range | >99% |
21
Tocris Bioscience™ Deschloroclozapine
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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High affinity and highly potent activator of hM3Dq and hM4Di DREADDs; rapidly blood brain barrier penetrant
| Target | DREADD Activators |
|---|---|
| CAS | 7-7-1977 |
| Purity | 0.98 |
| Chemical Name or Material | 11-(4-Methyl-1-piperazinyl)-5 H-dibenzo[b,e][1,4 ]diazepine |
| Recommended Storage | Store at RT |
| Molecular Formula | C18H20N4 |
22
Tocris Bioscience™ CEPT Cocktail Kit
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Cell culture supplement for improving stem cell survival
23
Invitrogen™ BODIPY™ 505/515 (4,4-Difluoro-1,3,5,7-Tetramethyl-4-Bora-3a,4a-Diaza-s-Indacene)
With its nonpolar structure and long-wavelength absorption and fluorescence, BODIPY™ 505/515 can be used as a stain for netural lipids and as a tracer for oil and other nonpolar lipids.
Encompass Procurement Services
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Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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24
Tocris Bioscience™ Dorsomorphin dihydrochloride
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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CAS: 1219168-18-9 Molecular Formula: C24H27Cl2N5O
| CAS | 1219168-18-9 |
|---|---|
| Molecular Formula | C24H27Cl2N5O |
25
Tocris Bioscience™ DAPT
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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CAS: 208255-80-5 Molecular Formula: C23H26F2N2O4
| CAS | 208255-80-5 |
|---|---|
| Molecular Formula | C23H26F2N2O4 |
26
Tocris Bioscience™ SR 95531 hydrobromide
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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CAS: 104104-50-9 Molecular Formula: C15H18BrN3O3
| CAS | 104104-50-9 |
|---|---|
| Molecular Formula | C15H18BrN3O3 |
27
Tocris Bioscience™ MG 132
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Proteasome and calpain inhibitor. Inhibits NF-κB activation
28
Tocris Bioscience™ Retinoic acid
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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CAS: 302-79-4 Molecular Formula: C20H28O2
| CAS | 302-79-4 |
|---|---|
| Molecular Formula | C20H28O2 |
29
Tocris Bioscience™ DAPI
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Fluorescent DNA stain
| Target | Fluorescent DNA Stains |
|---|---|
| CAS | 28718-90-3 |
| Purity | 0.95 |
| Chemical Name or Material | 2-[4-(Aminoiminomethyl)phenyl]-1 H-Indole-6-carboximidamide hydrochloride |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C16H15N50.2 HCl |
| Formula Weight | 350.25 |
30
Tocris Bioscience™ AMP PNP
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Kir6 blocker; non-hydrolyzable AMP analog