Bioactive Small Molecules
A vast array of small, non-peptide, organic compounds that are biologically active. Products include receptor antagonists, molecular probes, metabolites, GPCR ligands, neurotransmitters, ion channel modulators, and signaling activators and inhibitors.
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16
Tocris Bioscience™ Yoda 1
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Piezo1 channel activator
| Target | Other Calcium Channel Activators |
|---|---|
| CAS | 448947-81-7 |
| Purity | >99% |
| Chemical Name or Material | 2-[5-[[(2,6-Dichlorophenyl)methyl]thio]-1,3,4-thiadiazol-2-yl]pyrazine |
| Recommended Storage | Store at 4°C |
| Molecular Formula | C13H8Cl2N4S2 |
| Formula Weight | 355.27 |
17
Tocris Bioscience™ Y-27632 in solution
Sterile-filtered 10mM solution of Y-27632 pre-dissolved in water
18
Tocris Bioscience™ PEI STAR-Go™ transfection reagent
Aqueous solution of polyethylenimine (PEI) transfection reagent
| Target | Transfection Reagent |
|---|---|
| CAS | 49553-93-7 |
| Chemical Name or Material | Poly[imino(1,2-ethanediyl)] hydrochloride |
| Recommended Storage | Store at +4°C |
19
Tocris Bioscience™ Bortezomib
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High affinity proteasome inhibitor
| Target | Proteasome Inhibitors |
|---|---|
| CAS | 179324-69-7 |
| Purity | 0.98 |
| Chemical Name or Material | B-[(1 R)-3-Methyl-1-[[(2 S)-1-oxo-3-phenyl-2-[(2-pyrazinylcarbonyl)amino]propyl]amino]butyl]boronic acid |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C19H25BN4O4 |
20
Tocris Bioscience™ Poly(I:C)
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CAS: 24939-03-5 Molecular Formula: C19H27N7O16P2
| CAS | 24939-03-5 |
|---|---|
| Molecular Formula | C19H27N7O16P2 |
21
Tocris Bioscience™ Hoechst 33342
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CAS: 875756-97-1 Molecular Formula: C27H31Cl3N6O
| CAS | 875756-97-1 |
|---|---|
| Molecular Formula | C27H31Cl3N6O |
22
Tocris Bioscience™ HADA
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Fluorescent Probes for Imaging Bacteria
23
Tocris Bioscience™ dTAG-13
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Degrades mutant FKBP12F36V fusion proteins; useful alternative to genetic methods for target validation
24
Tocris Bioscience™ SB 431542
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Potent, selective inhibitor of TGF-βRI, ALK4 and ALK7
| CAS | 301836-41-9 |
|---|---|
| Recommended Storage | Store at Room Temperature |
| Molecular Formula | C22H16N4O3 |
| Formula Weight | 384.39 |
25
Tocris Bioscience™ Cytochalasin D
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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CAS: 22144-77-0 Molecular Formula: C30H37NO6
| CAS | 22144-77-0 |
|---|---|
| Molecular Formula | C30H37NO6 |
26
Tocris Bioscience™ QX 314 chloride
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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CAS: 1-4-5370 Molecular Formula: C11H18ClNO
| CAS | 1-4-5370 |
|---|---|
| Molecular Formula | C11H18ClNO |
27
Tocris Bioscience™ TPPB
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CAS: 497259-23-1 Molecular Formula: C27H30F3N3O3
| CAS | 497259-23-1 |
|---|---|
| Molecular Formula | C27H30F3N3O3 |
28
Tocris Bioscience™ PEI STAR™ transfection reagent
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Polyethylenimine (PEI) transfection reagent, chemically-defined
| Target | Transfection Reagent |
|---|---|
| CAS | 49553-93-7 |
| Chemical Name or Material | Poly[imino(1,2-ethanediyl)] hydrochloride |
| Recommended Storage | Store the unopened product at room temperature. Do not use past expiration date. |
29
Tocris Bioscience™ Mitomycin C
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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CAS: 50-07-7 Molecular Formula: C15H18N4O5
| CAS | 50-07-7 |
|---|---|
| Molecular Formula | C15H18N4O5 |
30
Tocris Bioscience™ Chloroquine diphosphate
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CAS: 50-63-5 Molecular Formula: C18H32ClN3O8P2
| CAS | 50-63-5 |
|---|---|
| Molecular Formula | C18H32ClN3O8P2 |